FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, in particular to new conjugates of therapeutic antibodies; it can be used in medicine. The invention discloses conjugates of antibodies, which specifically bind to VEGF, to hyaluronic acid (HA) polymer. Such conjugates show increased stability and increased time of half-life from the subject’s body.
EFFECT: invention can be used in medical practice for the treatment of diseases related to pathological angiogenesis, in particular eye diseases.
160 cl, 4 ex, 10 tbl, 14 dwg
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