SCHEMES FOR TREATMENT OF HIV-INFECTIONS AND AIDS Russian patent published in 2022 - IPC A61K31/4985 A61K31/505 A61P31/18 

FIELD: medicine; therapy.

SUBSTANCE: group of inventions relates to the field of medicine, namely to therapy and infectious diseases; it is intended for HIV treatment. A method for the treatment of HIV includes intramuscular administration to a subject of either 400 mg of cabotegravir or its pharmaceutically acceptable salt and 600 mg of rilpivirine or its pharmaceutically acceptable salt every four weeks or once a month in two separate injections of 2 ml, or 600 mg of cabotegravir or its pharmaceutically acceptable salt and 900 mg of rilpivirine or its pharmaceutically acceptable salt, injected every 8 weeks or every two months in two separate injections of 3 ml. A method for modification of an anti-HIV administration scheme for a subject who needs it is also presented, including: termination of administration to the subject of the first oral anti-HIV scheme; and intramuscular administration to the subject once a month or every four weeks of a dosage form consisting of 600 mg of rilpivirine or its pharmaceutically acceptable salt in an injection of 2 ml and 400 mg of cabotegravir or its pharmaceutically acceptable salt in an injection of 2 ml. In addition, a method for modification of an anti-HIV administration scheme for a subject who needs it is presented, including: termination of administration to the subject of the first oral anti-HIV scheme; and intramuscular administration to the subject every two months or every eight weeks of a dosage form consisting of 900 mg of rilpivirine or its pharmaceutically salt in an injection of 3 ml and 600 mg of cabotegravir or its pharmaceutically acceptable salt in an injection of 3 ml.

EFFECT: use of the group of inventions provides safe and effective HIV treatment.

15 cl, 4 dwg, 5 tbl