FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention relates to use of 8-chloro-N-(4-(trifluoromethoxy)phenyl)quinoline-2-amine or its N-glucuronide metabolite (1), or any of their pharmaceutically acceptable salts for treating or preventing HIV infection or AIDS in a patient for whom ineffectiveness or reduced effectiveness of previous treatment of HIV infection. Invention also relates to other applications of 8-chloro-N-(4-(trifluoromethoxy)phenyl)quinoline-2-amine or its N-glucuronide metabolite.
(1).
EFFECT: proposed use of 8-chloro-N-(4-(trifluoromethoxy)phenyl)quinoline-2-amine or its N-glucuronide metabolite (1) enables reducing a viral load in a patient infected with HIV, with prolonged effect and absence of resistance.
6 cl, 8 dwg, 2 tbl, 3 ex
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