FIELD: biotechnology.
SUBSTANCE: invention relates to methods for determination of whether a patient with an oncological disease, having tumor positive by a tumor antigen, responds to treatment, using an antibody against a tumor antigen, and methods for determination of whether a patient with an oncological disease, having tumor positive by a tumor antigen, will have a progression-free survival period. In this case, the tumor antigen is CLDN18.2 protein. A method for the treatment of a patient with an oncological disease, having tumor positive by an antigen, is also presented.
EFFECT: invention allows for its effective use for prediction of the efficiency of treatment of malignant neoplasms and prediction of clinical outcomes for patients with oncological diseases.
16 cl, 14 dwg, 16 tbl, 3 ex
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