FIELD: biotechnology.
SUBSTANCE: group of inventions including a bispecific agent that binds claudin 6 (CLDN6) and CD3, a recombinant nucleic acid, a host cell for the expression of a bispecific agent, the use of a bispecific agent, a recombinant nucleic acid or a host cell for the manufacture of a pharmaceutical composition for the treatment or prevention of cancer, characterized by cancer cells expressing CLDN6, a pharmaceutical composition for treating or preventing cancer characterized by cancer cells expressing CLDN6 and a method for treating or preventing a cancer characterized by cancer cells expressing CLDN6 are described.
EFFECT: invention expands the arsenal of agents binding to claudin 6 (CLDN6) and CD3.
21 cl, 54 dwg, 12 tbl, 34 ex
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Authors
Dates
2023-06-30—Published
2013-11-12—Filed