FIELD: biochemistry.
SUBSTANCE: invention relates to a binding agent that binds to the T-cell specific antigen CD3 and claudin 6 (CLDN6). Also disclosed is a nucleic acid or a mixture of nucleic acids encoding the said agent; a host cell containing the said nucleic acid; a vector or composition of vectors containing the said nucleic acid; a host cell containing the said nucleic acid; and a pharmaceutical composition containing the said agent. The use of the specified binding agent as a drug, and a method for the treatment or prevention of cancer, using the specified agent are disclosed.
EFFECT: invention makes it possible to effectively treat diseases associated claudin 6 expression.
34 cl, 14 ex, 10 tbl, 18 dwg
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Authors
Dates
2023-06-30—Published
2017-09-20—Filed