FIELD: organic chemistry and pharmaceuticals.
SUBSTANCE: invention relates to the field of organic chemistry and pharmaceuticals, and in particular to the use of biologically active substances of the class of substituted 3-imino(gadrazono)-3H-furan-2-ones. The use of N-(2-oxo-5-(4-chlorophenyl)furan-3(2H)-ylidene)-4-nitrobenzohydrazide 1 formula as a drug with anti-inflammatory activity is disclosed.
EFFECT: invention provides pronounced anti-inflammatory activity with low toxicity.
1 cl, 1 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 1-(4-METHOXYPHENYL)2-(2-(4-NITROBENZOYL)HYDRASONO)-4-OXO-4-(4-METHYLPHENYL)BUTANOIC ACID ETHYL ETHER WITH ANTI-INFLAMMATORY ACTIVITY | 2022 |
|
RU2798428C1 |
| 2-(2-(4-NITROBENZOYL)HYDRAZONO)-4-OXO-4-PHENYLBUTANOIC ACID 4-METHYLBENZYL ETHER WITH ANTI-INFLAMMATORY ACTIVITY | 2022 |
|
RU2798431C1 |
| 1-AMINO-1,6-DIOXO-6-(4-CHLOROPHENYL)-2-CYANO-4-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)HEXA -2,4-DIEN-3-OLATE POTASSIUM WITH ANTI-INFLAMMATORY ACTIVITY | 2022 |
|
RU2798468C1 |
| 2-(2-(4-NITROBENZOYL)HYDRASONO)-4-OXO-4-(4-METHYLPHENYL)BUTANOIC ACID OCTYL ETHER WITH ANALGESIC ACTIVITY | 2022 |
|
RU2798427C1 |
| 1-PHENYLETHYL ETHER OF 2-(2-(4-NITROBENZOYL)HYDRAZONO)-4-OXO-4-(4-METHYLPHENYL)BUTANOIC ACID WITH ANALGESIC ACTIVITY | 2022 |
|
RU2798430C1 |
| APPLICATION OF 2-[(3-(AMINOCARBONIL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO]-4-OXO-4-(4-CHLOROPHENYL)BUT-2-ENOIC ACID IN AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2785780C1 |
| APPLICATION OF 4-(4-BROMOPHENYL)-2-[2-(4-NITROBENZOYL)HYDRAZONO]-4-OXOBUTANOIC ACID AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2785781C1 |
| N-(5-BROMOPYRIDIN-2-YL)-4-OXO-4-(P-TOLYL)-2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL) )AMINO)BUT-2-ENAMIDE AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2798426C1 |
| 2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO)-4-(4-METHOXYPHENYL)-4-OXOBUT-2-ENOIC ACID WITH ANTI-INFLAMMATORY ACTIVITY | 2022 |
|
RU2784434C1 |
| 4-OXO-N-(FURAN-2-YLMETHYL)-4-(4-CHLOROPHENYL)-2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)BUT-2-ENAMIDE WITH ANALGESIC ACTIVITY | 2022 |
|
RU2798425C1 |
