FIELD: organic chemistry and pharmacology.
SUBSTANCE: invention relates to the field of organic chemistry and pharmacology, namely to a biologically active substance of the class of substituted 2-amino-4-oxobutanoic acids. Disclosed is 2-(2-(4-nitrobenzoyl)hydrazono)-4-oxo-4-(4-methylphenyl)butanoic acid 1-(4-methoxyphenyl)ethyl ester of formula 1, which has anti-inflammatory activity.
EFFECT: invention provides pronounced anti-inflammatory activity with low toxicity.
1 cl, 2 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 2-(2-(4-NITROBENZOYL)HYDRASONO)-4-OXO-4-(4-METHYLPHENYL)BUTANOIC ACID OCTYL ETHER WITH ANALGESIC ACTIVITY | 2022 |
|
RU2798427C1 |
| 1-PHENYLETHYL ETHER OF 2-(2-(4-NITROBENZOYL)HYDRAZONO)-4-OXO-4-(4-METHYLPHENYL)BUTANOIC ACID WITH ANALGESIC ACTIVITY | 2022 |
|
RU2798430C1 |
| 2-(2-(4-NITROBENZOYL)HYDRAZONO)-4-OXO-4-PHENYLBUTANOIC ACID 4-METHYLBENZYL ETHER WITH ANTI-INFLAMMATORY ACTIVITY | 2022 |
|
RU2798431C1 |
| APPLICATION OF N-(2-OXO-5-(4-CHLOROPHENYL)FURAN-3(2H)-YLYDENE)-4-NITROBENZOHYDRAZIDE AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2785782C1 |
| N'-(IMINO(2-((6-(2-METHOXYPHENYL)-2-(4-NITROBENZOYL)-3-OXO-2,3-DIHYDROPYRIDAZIN-4-YL)AMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-3-YL)METHYL)-4-NITROBENZOHYDRAZIDE, HAVING ANTI-INFLAMMATORY ACTIVITY | 2024 |
|
RU2831250C1 |
| APPLICATION OF 4-(4-BROMOPHENYL)-2-[2-(4-NITROBENZOYL)HYDRAZONO]-4-OXOBUTANOIC ACID AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2785781C1 |
| N-(5-BROMOPYRIDIN-2-YL)-4-OXO-4-(P-TOLYL)-2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL) )AMINO)BUT-2-ENAMIDE AS AN ANTI-INFLAMMATORY DRUG | 2022 |
|
RU2798426C1 |
| 2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO)-4-(4-METHOXYPHENYL)-4-OXOBUT-2-ENOIC ACID WITH ANTI-INFLAMMATORY ACTIVITY | 2022 |
|
RU2784434C1 |
| 4-OXO-2-{[4-PHENYL-3-(ETHOXYCARBONYL)THIOPHEN-2-YL]AMINO)}-4-(4-FLUOROPHENYL)BUT-2-ENOIC ACID, HAVING ANTI-INFLAMMATORY ACTIVITY | 2024 |
|
RU2831129C1 |
| 4-(4-METHYLPHENYL)-4-OXO-2-[3-(ETHOXYCARBONYL-4,5-R,R-THIOPHEN-2-YLAMINO]BUT-2-ENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | 2008 |
|
RU2389724C1 |
