FIELD: MiniTrap aflibercept obtaining.
SUBSTANCE: invention relates to efficient methods for obtaining MiniTrap aflibercept from a clarified harvest of a cell cultured in a chemically defined medium (COS) and expressing aflibercept, which provides a reduction in yellow-brown color during the production of MiniTrap aflibercept.
EFFECT: improvement of methods for obtaining MiniTrap aflibercept.
28 cl, 59 dwg, 9 tbl, 9 ex
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