BIFUNCTIONAL PROTEINS COMBINING CHECKPOINT BLOCKADE FOR TARGETED THERAPY Russian patent published in 2021 - IPC C07K16/22 C07K14/71 A61K39/395 G01N33/574 A61P35/00 

Abstract RU 2756899 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to a bispecific antibody for treating cancer, e.g., such as prostate cancer, lung cancer, NSCLC, melanoma, lymphoma, breast cancer, head and neck cancer, RCC, or ovarian cancer. The bispecific antibody comprises a binding domain binding a cell surface protein and a domain for inhibiting vascular endothelial growth factor (VEGF).

EFFECT: antibody applicable for treating different types of cancer.

16 cl, 16 dwg, 7 ex

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RU 2 756 899 C1

Authors

Her, Jeng-Horng

You, Jhong-Jhe

Hsu, Ching-Hsuan

Huang, Po-Lin

Dates

2021-10-06Published

2019-02-27Filed