METHOD FOR DIAGNOSING DISORDERS OF CEREBROSPINAL FLUID CIRCULATION IN PREMATURE INFANTS Russian patent published in 2022 - IPC A61B5/00 G01N33/483 

FIELD: medicine.

SUBSTANCE: invention relates to the field of medicine, in particular to neurosurgery. Ventricular and lumbar tests of infusion hydrodynamic load are carried out with the introduction of saline bolus in the volume of the age-related amount of cerebrospinal fluid in terms of body mass index, but no more than 10 ml. The effectiveness of pressure recovery is evaluated taking into account the volume of fast and slow movements of the cerebrospinal fluid through the Sylvian aqueduct of the brain. At the same time, during the ventricular test, the recovery of pressure is evaluated 1 minute after the introduction of the bolus. When registering pressure in accordance with the age-related physiological norm, a complete restoration of the outflow of cerebrospinal fluid from the ventricles is judged. With an increase in pressure by 30-50%, an incomplete recovery of the outflow of cerebrospinal fluid is diagnosed. With an increase in pressure of more than 50% of the age-related physiological norm, the absence of recovery of the outflow of cerebrospinal fluid is judged. If a complete and incomplete recovery of the outflow of cerebrospinal fluid is detected, a lumbar test of the infusion hydrodynamic load is performed, evaluating the effectiveness of the absorption of cerebrospinal fluid with pressure control 60 minutes after the bolus is administered. When registering the pressure in accordance with the age-related physiological norm, the complete absorption of the cerebrospinal fluid is judged. With an increase in pressure by 30-50%, incomplete recovery of suction is diagnosed. With an increase in pressure of more than 50% of the age-related physiological norm, the absence of restoration of the absorption of cerebrospinal fluid is judged. If there is no recovery of the outflow of cerebrospinal fluid, the lumbar test is not performed, but a repeated ventricular puncture with a needle with a diameter of 14 G is performed.

EFFECT: method makes it possible to increase the accuracy and informativeness of early diagnosis of cerebrospinal fluid disorders in hydrocephalus in premature infants, optimize the management tactics of such patients, eliminate the risk of inflammatory complications without the need for long-term monitoring, and improve the quality of life.

1 cl, 1 tbl, 2 ex