METHOD FOR ASSESSMENT OF EFFICIENCY OF TREATMENT WITH INTRAVENOUS IMMUNOGLOBULINS IN PATIENTS WITH HABITUAL MISCARRIAGE AND CIRCULATION OF ANTIPHOSPHOLIPID ANTIBODIES Russian patent published in 2022 - IPC G01N33/53

Abstract RU 2786456 C1

FIELD: medicine; obstetrics and gynecology.

SUBSTANCE: invention relates to medicine, namely to obstetrics and gynecology; it can be used for assessment of the efficiency of treatment with intravenous immunoglobulins in patients with habitual miscarriage and circulation of antiphospholipid antibodies. For this purpose, immunohistochemical examination of the placenta is carried out by determination of a relative area of expression of an endothelial CD 34+ marker, which is calculated according to the formula

where S% is the relative area of expression of the endothelial CD 34+ marker; S positive is a value of an area of immune-positive cells; S total is a value of a preparation area. The efficiency of treatment is confirmed, when obtaining a value of the relative area of expression of the endothelial CD 34+ marker, equal to 14% or more.

EFFECT: accurate and reliable assessment of the efficiency of treatment.

1 cl, 3 ex

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RU 2 786 456 C1

Authors

Eremeeva Dina Rustemovna

Dates

2022-12-21—Published

2021-08-27—Filed