FIELD: medicine.
SUBSTANCE: invention refers to medicine, particularly to obstetrics and gynaecology, and can be used to predict the risk of developing chronic placental insufficiency at 6-8 weeks of pregnancy in women with circulating APLAs (antiphospholipid antibodies) and a burdened obstetric anamnesis. Blood soluble fms-like tyrosine kinase (sFlt), placental growth factor (PlGF), endoglin, CD11b on platelet-monocyte complexes, CD40 on platelet-monocyte complexes, antibodies to β2-glycoprotein. Further, the risk of developing chronic placental insufficiency is calculated by formula. At P≥50% predict a high risk of developing, and if R≤49% – low risk of developing disease.
EFFECT: method enables predicting the development of chronic placental insufficiency by assessing the complex of the most significant indicators.
1 cl, 2 dwg, 2 tbl, 3 ex
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