INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR Russian patent published in 2022 - IPC A61K31/44 A61K31/444 A61K31/4439 A61K31/505 A61K31/506 A61K31/5377 C07D213/74 C07D239/42 C07D401/06 C07D401/10 C07D403/06 C07D403/10 C07D413/10 A61P35/00 A61P35/02 

Abstract RU 2786524 C2

FIELD: medicine.

SUBSTANCE: present group of inventions relates to new compounds of the formula I

,

their pharmaceutically acceptable salts, as well as to a pharmaceutical composition, a method for inhibition of biological activity of an epidermal growth factor receptor (hereinafter – EGFR), a method for the treatment of diseases or disorders mediated by EGFR activity, and the use of the claimed compounds or the specified composition for the treatment of a disease or a disorder mediated with EGFR activity.

EFFECT: obtaining an inhibitor for an epidermal growth factor receptor.

16 cl, 14 ex, 16 tbl

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RU 2 786 524 C2

Authors

Zavyalov Kirill Vadimovich

Gorbunova Svetlana Leonidovna

Shekhovtsov Artem Evgenevich

Kasatkina Mariya Andreevna

Beketova Darya Dmitrievna

Kozhemyakina Natalya Vladimirovna

Kulish Kirill Igorevich

Maksimenko Elena Aleksandrovna

Meleshina Marina Viktorovna

Melchaeva Olga Anatolevna

Mindich Aleksej Leonidovich

Morozov Dmitrij Valentinovich

Popkova Aleksandra Vladimirovna

Smetanin Ilya Alekseevich

Silonov Sergej Aleksandrovich

Soldatova Yaroslavna Aleksandrovna

Yakobson Georgij Viktorovich

Dates

2022-12-21Published

2018-09-28Filed