EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITORS Russian patent published in 2024 - IPC C07D403/02 C07D213/06 A61K31/33 A61K31/397 A61P35/00 

FIELD: biotechnology.

SUBSTANCE: group of inventions relates to a compound of formula I or a stereoisomer thereof, also relates to a method of inhibiting biological activity of an epidermal growth factor receptor (EGFR) in a subject, also relates to a pharmaceutical composition containing a compound of formula I or a stereoisomer thereof and one or more pharmaceutically acceptable excipients for preventing or treating a disease or disorder mediated by EGFR activity, also relates to a method of treating a disease or disorder mediated by EGFR activity, comprising administering in a therapeutically effective amount of a compound of formula I or a stereoisomer thereof or a pharmaceutical composition to a subject in need of such treatment, also relates to use of a compound of formula I or a stereoisomer thereof or a pharmaceutical composition for treating a disease or disorder mediated by EGFR activity in a subject in need of such treatment.

EFFECT: group of inventions provides developing new inhibitors of epidermal growth factor receptor (EGFR) and using them for treating a disease or disorder mediated by EGFR activity.

28 cl, 8 tbl, 54 ex