FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to experimental ophthalmology, and can be used to simulate neurodegenerative processes in the eye. For this, an intravitreal injection of the neurotoxin 6-OHDA to the rabbit in a solution of 0.9% sodium chloride containing ascorbic acid at a concentration of 0.5% is carried out. At the same time, 6-OHDA is administered twice with an interval of 2 hours, 100 mcg in a solution of 50 mcl.
EFFECT: invention provides a well-reproducible and reversible neurodegenerative process in the eye of a rabbit.
1 cl, 1 dwg, 2 ex
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Authors
Dates
2023-01-09—Published
2022-06-03—Filed