METHOD FOR PREDICTING CONGENITAL INFECTIOUS DISEASES OF CHLAMYDIAL ETIOLOGY IN A NEWBORN IN PREGNANT WOMEN WITH ACUTE CHLAMYDIAL INFECTION Russian patent published in 2023 - IPC G01N33/68 G01N33/487 G01N33/561 G01N33/569 G01N33/573 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely obstetrics and gynecology, and can be used to predict congenital infectious diseases of chlamydial etiology in a newborn in pregnant women with acute chlamydial infection. Amniotic fluid of pregnant women with acute chlamydia infection, venous blood of pregnant women for lactoferrin content, levels of alpha2-macroglobulin and alpha1-antitrypsin are studied. Additionally, in the amniotic fluid of pregnant women with acute chlamydial infection, the albumin content is determined by rocket immunoelectrophoresis using a monospecific antiserum. At blood serum concentrations of alpha2-macroglobulin more than 3.34 g/l, alpha1-antitrypsin more than 3.84 g/l, lactoferrin more than 5.29 mg/l, in amniotic fluid alpha2-macroglobulin more than 37.5 mg/l, lactoferrin more than 4.13 mg/l, albumin more than 5.03 g/l the presence of congenital infectious diseases chlamydial etiology in a newborn is predicted. When the concentration in the blood serum of pregnant women with acute chlamydial infection of alpha2-macroglobulin is less than or equal to 3.34 g/l, alpha1-AT is less than or equal to 3.84 g/l, lactoferrin is less than or equal to 5.29 mg/l, in amniotic fluid alpha2-MG is less than or equal to 37.5 m/l, lactoferrin is less than or equal to 4.13 mg/l, albumin less than or equal to 5.03 g/l the absence of congenital infectious diseases of chlamydial etiology in a newborn is predicted.

EFFECT: method makes it possible to increase the effectiveness of predicting the outcome of pregnancy for the fetus in women with acute chlamydial infection by predicting congenital infectious diseases of the newborn in pregnant women with chlamydial infection by determining the content of a number of biochemical parameters in the amniotic fluid and blood of pregnant women at the antenatal stage.

1 cl, 2 ex