COMPOSITIONS AND METHODS FOR TREATMENT OF LUNG EMPHYSEMA AND OTHER FORMS OF COPD Russian patent published in 2023 - IPC A61K31/30 A61K31/726 A61K31/727 A61K31/728 A61K33/34 A61P11/00 A61P11/08 

FIELD: pharmacology.

SUBSTANCE: group of inventions relates to the field of pharmacotherapy and concerns a combination for the lung emphysema treatment and treatment method. The combination contains an active agent containing a copper compound, where the copper compound is copper sulfate, in an amount of about 0.5 mg to about 1 mg, and glycosaminoglycan or its physiologically acceptable salt, where glycosaminoglycan is heparin, in an amount of about 150,000 IU. A method for treating a subject suffering from lung emphysema involves the administration by inhalation to said subject of a combination containing a copper compound, where the copper compound is copper sulfate, in an amount of about 0.5 mg to about 1 mg, and glycosaminoglycan or its physiologically acceptable salt, where glycosaminoglycan is heparin, in an amount of about 150,000 IU.

EFFECT: beneficial effect on the restoration and development of elastin fibers in the lungs of patients with emphysema while preventing copper-induced stimulation of collagen crosslinking.

13 cl, 17 dwg