ANTIBODIES AND ANTIBODY-DRUG CONJUGATES SPECIFIC TO CD123 AND THEIR USE Russian patent published in 2023 - IPC C07K16/28 A61K39/395 A61P35/00 

Abstract RU 2789150 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, in particular to an isolated antibody, which specifically binds to CD123, as well as to a conjugate containing it and a composition. Isolated polynucleotide encoding the above-mentioned antibody, as well as a cell and a vector containing it are also disclosed. The invention also relates to a method for the production of an antibody, providing cultivation of the above-mentioned cell.

EFFECT: invention is effective for the treatment of a condition related to cells expressing CD123.

39 cl, 3 dwg, 16 tbl, 6 ex

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RU 2 789 150 C2

Authors

Charati, Manoj Baburao

Han, Yoon-Chi

Katragadda, Madan

Piche-Nicholas, Nicole Melissa

Tumey, Lawrence Nathan

Dates

2023-01-30Published

2018-10-16Filed