FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, in particular to a single variable immunoglobulin domain capable of specifically binding to human serum albumin, its production method, as well as to a structure containing it and a method for the production of a structure. Nucleic acid encoding the above-mentioned domain, as well as nucleic acid encoding the above-mentioned structure are also disclosed. The invention also relates to an expression genetic structure and a host cell, containing the above-mentioned nucleic acid.
EFFECT: invention is effective for provision of an increase in half-life of therapeutic compounds, molecules, or structures.
24 cl, 7 dwg, 2 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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| POLYPEPTIDES BINDING TO ADAMTS5, MMP13, AND AGGRECAN | 2018 |
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RU2730671C2 |
