METHOD OF TOTAL IRRADIATION OF THE BONE MARROW AND LYMPHATIC SYSTEM Russian patent published in 2023 - IPC A61N5/10 

FIELD: medicine; radiotherapy.

SUBSTANCE: invention can be used for total irradiation of the bone marrow and lymphatic system. Apply the technique of rotational radiation therapy, modulated by volume. When planning, not the whole body is used as a target, but the bone marrow and lymphatic system. It optimizes the dose in the risk organs: lenses, lungs and kidneys, as well as additionally in the heart, liver, bladder and intestines. Calculate upper and lower body plans with dose escalation to the bone marrow. At the same time, the docking of radiation fields between a series of images of the upper body of the patient and a series of images of the lower body of the patient is carried out in such a way that when creating a plan for a series of images of the upper body of the patient in the docking zone, the target is divided into 5 consecutive volumes, which receive dose values of 91, 7%, 75%, 50%, 25%, 8.3% of prescription per target. The same volumes are then isolated on a series of images of the lower body of the patient, which receive dose values of 8.3%, 25%, 50%, 75%, 91.7% of the target prescription. Moreover, in the plan for the lower part of the body, coplanar 3600 arches with an energy of photon beams of 6 MeV are used, supplied by VMAT technology, moving clockwise and counter-clockwise, with different positions of isocenters, differing from each other only in the position of the longitudinal coordinate. Then the patient is irradiated on a linear accelerator.

EFFECT: method provides effective and safe radiation treatment of patients with various malignant and non-malignant diseases by reducing the radiation dose in organs at risk, improving the method of joining radiation fields between series of images of the upper and lower parts of the patient's body, which makes it possible to uniformly and safely irradiate the docking area by reducing the influence of possible shift of the patient along the longitudinal axis during treatment on the final dose distribution.

1 cl, 4 dwg, 1 ex