ANTIGEN RECEPTORS AND THEIR APPLICATIONS Russian patent published in 2023 - IPC C07K14/705 C07K19/00 C12N5/783 C12N5/22 C12N15/09 A61K35/17 A61P35/00 

Abstract RU 2792042 C2

FIELD: biotechnology.

SUBSTANCE: claimed invention: an antigenic receptor for providing an immune response to cancer cells expressing a tumour antigen, the receptor contains a first peptide chain and a second peptide chain, a recombinant CD8+ T host cell expressing the antigen receptor and a method for its production, a nucleic acid, a pharmaceutical formula and method for treating cancer.

EFFECT: invention allows to use it in the treatment of malignant tumours by targeting cells expressing the antigen on the cell surface, where the tumour antigen is claudin 6.

13 cl, 18 dwg, 5 ex

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RU 2 792 042 C2

Authors

Foss, Ralf Kholger

Zakhin, Ugur

Teobald, Mattias

Simon, Petra

Birtel, Mattias

Dates

2023-03-16Published

2016-10-05Filed