FIELD: biotechnology.
SUBSTANCE: invention relates to an antibody or antigen-binding fragment that specifically binds to tumour necrosis factor 2 (TNFR2); to a pharmaceutical composition and a set for cancer treatment containing the said antibody; a method for treating a disease associated with an immune disorder; to the use of said antibody, or an antigen-binding fragment thereof, or a pharmaceutical composition for the manufacture of a medicament for the treatment of a disease associated with an immune disorder; to a method for detecting soluble TNFR2 (sTNFR2) using the said antibody.
EFFECT: invention makes it possible to regulate the function of immune cells and can be used as a drug for the treatment of diseases associated with immune disorders, such as a tumor.
16 cl, 14 dwg, 10 tbl, 18 ex
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Authors
Dates
2023-03-29—Published
2020-07-31—Filed