METHOD FOR PRE-IMPLANTATION PROCESSING OF TEXTILE PRODUCTS FOR CARDIOVASCULAR SURGERY Russian patent published in 2023 - IPC A61K8/65 A61F2/02 A61F2/06 C07K14/78 

Abstract RU 2794740 C2

FIELD: cardiovascular surgery.

SUBSTANCE: invention relates to a method for pre-implantation processing of textile products for cardiovascular surgery. The claimed method consists in treating prostheses with a solution containing a gelling agent, followed by crosslinking with a crosslinking agent, characterized in that collagen, gelatin or a mixture thereof with a mass concentration of 2–15% is used as a gelling agent; as a crosslinking agent, 1,4-butanediol diglycidyl ether with a molecular weight of 202.4 Da or polyethylene glycol diglycidyl ether with a molecular weight of 500 Da, or polypropylene glycol diglycidyl ether with a molecular weight of 380 or 640 Da is used; while the mass concentration of the cross-linking agent is from 3% to 20%, and the treatment of prostheses with a solution containing a gelling agent is carried out at a temperature of 35°C to 55°C.

EFFECT: above method provides biopolymer coated textiles for use in cardiovascular surgery that have zero chemical porosity and will not use glutaraldehyde or formaldehyde in the manufacturing process.

2 cl, 1 tbl, 15 ex

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RU 2 794 740 C2

Authors

Venzhik Anton Nikolaevich

Nikolaev Denis Aleksandrovich

Romanova Irina Viktorovna

Dates

2023-04-24Published

2021-03-23Filed