FIELD: biotechnology.
SUBSTANCE: present invention relates to application of polypeptide labelled with radioactive 99mTc, for imaging expression of human epidermal growth factor receptor type 2 (HER2), and can be used in diagnosis of tumorous diseases.
EFFECT: invention enables to obtain a specifically binding to HER2 polypeptide conjugated with radionuclide and chelating agent, wherein introduction of radioactive group is carried out at final stage of synthesis of conjugate, which provides a high output of end product.
5 cl, 22 dwg, 10 tbl, 1 ex
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Authors
Dates
2016-07-27—Published
2011-12-19—Filed