RADIOACTIVE LABELLED PEPTIDES BINDING TO HER2 Russian patent published in 2016 - IPC C07K14/485 A61K103/10 G01N33/60 A61K51/08 C07K1/13 

Abstract RU 2592685 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to application of polypeptide labelled with radioactive 99mTc, for imaging expression of human epidermal growth factor receptor type 2 (HER2), and can be used in diagnosis of tumorous diseases.

EFFECT: invention enables to obtain a specifically binding to HER2 polypeptide conjugated with radionuclide and chelating agent, wherein introduction of radioactive group is carried out at final stage of synthesis of conjugate, which provides a high output of end product.

5 cl, 22 dwg, 10 tbl, 1 ex

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RU 2 592 685 C2

Authors

Syud Faisal

Lee Brian Duh-Lan

Zhang Rong

Iveson Peter

Schaffer Paul

Eriksson Tove

Genneriusson Elin

Frejd Fredrik

Abrahmsen Lars

Feldwisch Joachim

Herne Nina

Lendel Christofer

Dates

2016-07-27Published

2011-12-19Filed