COMBINATION OF RHODIOLA AND ASTRAGALUS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES Russian patent published in 2023 - IPC A61K36/481 A61K36/41 A61P25/16 A61P25/28 

Abstract RU 2804478 C2

FIELD: pharmaceutical industry.

SUBSTANCE: use of a product and a method for treating Alzheimer’s and/or Parkinson’s diseases. Use of a product containing rhodiola extract and astragalus extract as combined products for use in the treatment of Alzheimer's and/or Parkinson's disease, wherein the rhodiola extract is an extract of the roots of Rhodiola rosea, and the extract of astragalus is an extract of the roots of Astragalus membranaceus, where the Rhodiola rosea extract contains at least 1.5 wt.% rosavin based on the total weight of the dry extract of Rhodiola rosea, where the extract of Astragalus membranaceus contains at least 0.2% of the wt.% astragalosides and at least 10 wt.% polysaccharides based on the total weight of the dry extract of Astragalus membranaceus and where the mass ratio in terms of dry matter of the extract of astragalus to the extract of Rhodiola is from 0.5 to 1.5. A method for treating Alzheimer's and Parkinson's diseases, comprising administering a dose of 50 mg/day to 500 mg/day of Rhodiola rosea extract through a product containing Rhodiola extract and Astragalus extract as combination products, wherein the Rhodiola extract is an extract of Rhodiola rosea roots, and this extract astragalus is an extract of the roots of Astragalus membranaceus, where the extract of Rhodiola rosea contains at least 1.5 wt.% rosavin based on the total weight of the dry extract of Rhodiola rosea, and where the extract of Astragalus membranaceus contains at least 0.2 wt.% of astragalosides and at least 10 wt.% polysaccharides based on the total weight of the dry extract of Astragalus membranaceus and where the mass ratio, based on the dry matter of the astragalus extract to the rhodiola extract, is from 0.5 to 1.5.

EFFECT: above use of the product and method for treating Alzheimer's and/or Parkinson's diseases makes it possible not only to maintain the length of axons in a model of a neurodegenerative disease, but also to achieve their elongation.

8 cl, 11 dwg, 3 tbl, 5 ex

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RU 2 804 478 C2

Authors

Goudet, Gerald

Dates

2023-10-02Published

2019-02-15Filed