METHOD OF PRODUCING ANTIHELMINTHIC 4-AMINO-QUINOLINE-3-CARBOXAMIDE DERIVATIVES Russian patent published in 2023 - IPC C07D215/54 C07D215/56 C07D405/12 C07D405/14 

Abstract RU 2804710 C2

FIELD: organic chemistry.

SUBSTANCE: group of inventions includes a method of obtaining compounds of formula (II) that effectively interact with Slo-1 and are used for the treatment and/or prevention of helminth infections. The meanings of substituents in formula (II) are as defined in the claims. The group of inventions also relates to a method of obtaining intermediate compounds and their use in a method of obtaining a compound of formula (II). The process for the preparation of compounds of formula (II) is carried out by carrying out steps B-a, B-b, B-c, B-d of the claims, provided that step B-d is not carried out before step B-c.

EFFECT: group of inventions makes it possible to achieve a high yield and purity of compounds of general formula (II).

46 cl, 2 ex

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RU 2 804 710 C2

Authors

Erver, Florian

Memmel, Frank

Khimmler, Tomas

Stajb, Andreas, Karl

Novakovski, Mark

Dates

2023-10-04Published

2018-12-14Filed