METHOD FOR PRODUCING [(3-HYDROXYPYRIDINE-2-CARBONYL)AMINO]ALKANE ACIDS, ESTERS AND AMIDES Russian patent published in 2022 - IPC C07D213/79 C07D213/81 

FIELD: medicine.

SUBSTANCE: invention relates to a compound having the formula (1), where R¹ is ring selected from 3,4-difluorophenyl, 3,5-difluorophenyl, 2-chlorophenyl, 3-chlorophenyl, 2,3-dichlorophenyl, 3,4-dichlorophenyl, 3-bromophenyl, 3,5-dichlorophenyl, 2,3,4-trifluorophenyl, 2,3,5-trifluorophenyl, 2,3,6-trifluorophenyl, 2,4,5-trifluorophenyl, 2,4,6-trifluorophenyl, 2,4-dichlorophenyl, 2,5-dichlorophenyl, 2,6-dichlorophenyl, 3,4-dichlorophenyl, 2,3,4-trichlorophenyl, 2,3,5-trichlorophenyl, 2,3,6-trichlorophenyl, 3,4,5-trichlorophenyl, 2,4,6-trichlorophenyl, 2-chloro-3-methylphenyl, 2-chloro-4-methylphenyl, 2-chloro-5-methylphenyl, 2-chloro-6-methylphenyl, 3-chloro-2-methylphenyl, 3-chloro-4-methylphenyl, 3-chloro-5-methylphenyl, 3-chloro-6-methylphenyl, 2-fluoro-3-methylphenyl, 2-fluoro-4-methylphenyl, 2-fluoro-5-methylphenyl, 2-fluoro-6-methylphenyl, 3-fluoro-2-methylphenyl, 3-fluoro-4-methylphenyl, 3-fluoro-5-methylphenyl and 3-fluoro-6-methylphenyl.

EFFECT: compounds intended for compound synthesis that can be used as prolyl hydroxylase inhibitors or for the treatment of conditions, in which prolyl hydroxylase inhibition is desirable.

5 cl, 3 dwg, 5 ex