NEW BICYCLIC PYRAZOLE DERIVATIVES Russian patent published in 2022 - IPC C07D513/04 A61K31/429 A61P33/10 

FIELD: medicine.

SUBSTANCE: invention relates to a compound of the general formula (I) or to its pharmaceutically acceptable salt, in which A is A1 or A2, o is 0, X, Y are independently selected from a group consisting of CR⁶R⁷, O, where at least one of X and Y is CR⁶R⁷, G is S, R¹ is selected from hydrogen, R² is selected from C₁-C₆-alkyl, R³ is selected from C₁-C₄-alkyl, R⁴ is selected from hydrogen, R⁵ is selected from hydrogen, R⁶ is hydrogen, R⁷ is hydrogen, Q is selected from phenyl, which is optionally substituted with 2 or 3 substitutes selected from a group consisting of halogen, C₁-C₄-halogenalkyl having from 1 to 3 halogen atoms, C₁-C₄-halogenalkoxy having from 1 to 3 halogen atoms, -N(C₁-C₄-alkyl)². The invention also relates to a method for the production of a compound of the formula (I), an intermediate compound used for the production of the specified compounds, a pharmaceutical composition based on a compound of the formula (I).

EFFECT: new compounds and a pharmaceutical composition based on them are obtained, which can be used in medicine for the treatment of a helminth infection caused by nematodes.

10 cl, 2 tbl, 15 ex