PHARMACEUTICAL COMPOUNDS Russian patent published in 2023 - IPC C07D263/48 A61K31/541 A61P29/00 A61P37/00 

Abstract RU 2805932 C2

FIELD: organic chemistry.

SUBSTANCE: compound of formula (1), where R1 represents hydrogen or fluorine, its pharmaceutically acceptable salts, application, method of treatment, pharmaceutical composition, method for obtaining a compound of Formula (1) by hydrolysis of a compound of Formula (15) in acidic conditions.

EFFECT: compound of Formula (VI) with inhibitory activity against TYK2 kinase.

23 cl, 9 tbl, 4 ex

Similar patents RU2805932C2

Title Year Author Number
2-PHENYL-OXAZOLE-4-CARBOXAMIDE DERIVATIVES, MODULATING ACTIVITY OF JAK AND TYK2 KINASE 2013
  • Rider Dzhon Charlz
RU2652795C2
AMINOPYRAZOLES AS SELECTIVE JANUS KINASE INHIBITORS 2017
  • Fuller, Peter, H
  • Brubaker, Jason
  • Young, Jonathan, R
RU2757218C2
NEW DERIVATIVES OF AMINOIMIDAZOPYRIMIDINE AS JANUS KINASE INHIBITORS AND PHARMACEUTICAL APPLICATION THEREOF 2019
  • Larsen, Jens C. Hojland
  • Larsen, Mogens
  • Ritzen, Andreas
RU2772463C1
TRIAZOLOPYRIDINE JAK INHIBITOR COMPOUNDS AND METHODS 2009
  • Chzhu Bin-Jan'
  • Siu Majkl
  • Magnuson Stiven R.
  • Pastor Richard
  • Khajin Kheh
  • Isun Sjao
  • Tszifu Chzhehn
  • Sin Sjuj
  • Tszjun'Pin Chzhao
  • Lju Vendi
RU2561104C2
JAK-INHIBITING TRIAZOLOPYRIDINE COMPOUNDS AND METHODS 2009
  • Chzhu Bin-Jan'
  • Siu Majkl
  • Magnuson Stiven R.
  • Pastor Richard
  • Khajin Kheh
  • Isun Sjao
  • Tszifu Chzhehn
  • Sin Sjuj
  • Tszjun'Pin Chzhao
  • Kharli Kristofer A.
  • Ljan Tszjun'
  • Lju Vendi
  • Lissikatos Dzhozef P.
RU2560153C2
PYRROLOPYRIMIDINE COMPOUNDS AND APPLICATION THEREOF 2011
  • Su Vehj-Go
  • Dehn Vehj
  • Li Tszin'Shuj
  • Tszi Tszjan'Go
RU2563644C2
HETEROCYCLIC COMPOUNDS FOR TYROSINE KINASE 2 ACTIVITY MEDIATION 2020
  • Chen, Syanyan
  • Pan, Yujchen
RU2826012C2
HETEROCYCLIC ANALOGUES OF PYRIMIDINES AS JAK INHIBITORS 2012
  • Frimen Dzhej
  • Rider Valeri
  • Ehddison Glinn
  • Rehmsden Najdzhel'
  • Skehnlon Dzhejn Ehlizabet
  • Kharrison Richard Dzhon
RU2564419C1
PYRAZOLPYRIMIDINE COMPOUNDS JAK INHIBITORS AND METHODS 2009
  • Blehjni Dzheffri
  • Gibbons Pol A.
  • Khanan Ehmili
  • Lissikatos Dzhozef P.
  • Magnuson Stiven R.
  • Pastor Richard
  • Rouson Tomas E.
  • Chzhou Ajkheh
  • Chzhu Bin-Jan'
RU2539568C2
AMINOPYRIMIDINYL DERIVATIVES 2021
  • Gerstenberger, Brajan Stefen
  • Tszyao, Venkhua
  • Lall, Mandzhinder Singkh
  • Lira, Rikardo
  • Shnute, Mark Edvard
RU2817349C1

RU 2 805 932 C2

Authors

Rider, Dzhon Charlz

Dates

2023-10-24Published

2019-10-07Filed