FIELD: pharmaceuticals; medicine.
SUBSTANCE: 1 object is a composition for obtaining an agent for intravaginal delivery of an active component, including at least one structure-forming polysaccharide selected from the group including polysaccharides biodegradable in the vaginal cavity, at least one mucoadhesive component, and at least one a pH modifier, which is an organic acid, as well as at least one active component taken in a therapeutically effective amount. Objects 2 and 3 – an agent for intravaginal delivery of the active component and a method of obtaining the medicinal product including preparing aqueous solutions of the components of the above composition, mixing them, freezing the resulting mixture, followed by freeze-drying. Object 4 – a method of intravaginal delivery of the active component, including the introduction of the product into the vagina.
EFFECT: obtaining a solid dosage form (agent) for vaginal administration, based on the use of a biodegradable polysaccharide as a structure-forming component, which has a set of properties and characteristics that increase the effectiveness of therapy while ensuring ease of use of an agent.
35 cl, 2 dwg, 4 tbl, 26 ex
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Authors
Dates
2023-10-26—Published
2022-04-21—Filed