AGENT FOR INTRAVAGINAL DELIVERY OF ACTIVE COMPONENT, METHOD OF PRODUCTION AND USE OF THE MEDICINAL PRODUCT Russian patent published in 2023 - IPC A61K9/00 A61K45/08 A61K47/12 A61K47/26 A61K47/36 A61P15/02 

Abstract RU 2806114 C2

FIELD: pharmaceuticals; medicine.

SUBSTANCE: 1 object is a composition for obtaining an agent for intravaginal delivery of an active component, including at least one structure-forming polysaccharide selected from the group including polysaccharides biodegradable in the vaginal cavity, at least one mucoadhesive component, and at least one a pH modifier, which is an organic acid, as well as at least one active component taken in a therapeutically effective amount. Objects 2 and 3 – an agent for intravaginal delivery of the active component and a method of obtaining the medicinal product including preparing aqueous solutions of the components of the above composition, mixing them, freezing the resulting mixture, followed by freeze-drying. Object 4 – a method of intravaginal delivery of the active component, including the introduction of the product into the vagina.

EFFECT: obtaining a solid dosage form (agent) for vaginal administration, based on the use of a biodegradable polysaccharide as a structure-forming component, which has a set of properties and characteristics that increase the effectiveness of therapy while ensuring ease of use of an agent.

35 cl, 2 dwg, 4 tbl, 26 ex

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RU 2 806 114 C2

Authors

Lozinskij Vladimir Iosifovich

Ivanov Roman Viktorovich

Zinchenko Arkadij Vladimirovich

Shobolov Dmitrij Lvovich

Strygin Aleksej Sergeevich

Dates

2023-10-26Published

2022-04-21Filed