PHARMACEUTICAL AGENT FOR INTRAVAGINAL ADMINISTRATION, METHOD FOR ITS PREPARATION AND USE Russian patent published in 2024 - IPC A61K9/00 A61K45/08 A61K47/12 A61K47/26 A61K47/36 A61P15/02 

FIELD: pharmaceutics; medicine.

SUBSTANCE: first object is a pharmaceutical agent for intravaginal administration, which is a solid volumetric body with a macroporous structure, after freezing and freeze drying, containing at least one structure-forming polysaccharide selected from a group, comprising polysaccharides biodegradable in the vaginal cavity, at least one mucoadhesive component, at least one pH modifier, which is an organic acid. Second object is a method of obtaining an agent, involving preparation of aqueous solutions of components of said agent, their mixing, freezing of the obtained mixture followed by freeze drying. Third object—use of said agent as an agent for intravaginal administration of an active ingredient for treating and/or preventing diseases of the female reproductive system.

EFFECT: obtaining a solid dosage form (agent) for vaginal administration, based on the use of a biodegradable polysaccharide as a structure-forming component, possessing a set of properties and characteristics providing convenience of using the agent.

23 cl, 2 dwg, 4 tbl, 26 ex