BIOPOLYMER MATRIX FOR INTRAVAGINAL ADMINISTRATION, METHOD FOR PREPARATION AND USE THEREOF Russian patent published in 2025 - IPC A61K9/00 A61K45/08 A61K47/12 A61K47/26 A61K47/36 A61P15/02 

FIELD: medicine; pharmaceutics.

SUBSTANCE: group of inventions refers to pharmaceutics and medicine. Object 1 is a composition for producing a biopolymer matrix comprising at least one structure-forming polysaccharide selected from the group, comprising polysaccharides biodegradable in the vaginal cavity, at least one mucoadhesive component and at least one pH modifier which is an organic acid. Objects 2 and 3 are a biopolymer matrix intended for intravaginal administration, which is a solid volumetric body with a macroporous structure, and a method for producing a biopolymer matrix comprising preparing aqueous solutions of components of said composition, mixing them, freezing the obtained mixture followed by lyophilisation. Object 4 is the use of a biopolymer matrix as an agent for intravaginal administration of an active component for the treatment or prevention of diseases of the organs of the female reproductive system.

EFFECT: obtaining a biopolymer matrix (agent) for vaginal administration, based on the use of a biodegradable polysaccharide as a structure-forming component, having certain set of properties and characteristics, providing ease of use of agent.

25 cl, 2 dwg, 4 tbl, 26 ex