FIELD: medicinal chemistry.
SUBSTANCE: invention includes a triazole derivative of general formula I or its spatial isomers. Where in formula IX1 and X2 represent halogen; R is selected from 4-(prop-1-en-2-yl)cyclohex-1-en-1-yl)methyl, 3,7-dimethyloctyl, 3,7-dimethyloctyl-6-en-1-yl, 3, 7-dimethyloct-2,6-dien-1-yl, (6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl or (6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethyl.
EFFECT: triazole derivatives with high broad-spectrum antifungal activity.
1 cl, 12 dwg, 1 tbl, 8 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ADAMANTYL-CONTAINING DERIVATIVES OF 1,2,4-TRIAZOLE AND 1,3,4-THIADIAZOLE HAVING MONOTERPENOID FRAGMENTS USED AS INHIBITORS OF THE ENZYME TYROSYL-DNA PHOSPHODIESTERASE 1 | 2020 |
|
RU2761880C1 |
| Chiral trifluoromethylated monoterpene thioacetates and myrtenal-based thiols | 2020 |
|
RU2743302C1 |
| TERPENE-BASED QUATERNARY AMMONIUM COMPOUNDS HAVING ANTIMICROBIAL ACTIVITY | 2023 |
|
RU2818914C1 |
| SULPHO-DERIVATIVES BASED ON BETA-PINENE AND A METHOD FOR PRODUCTION THEREOF | 2019 |
|
RU2708617C1 |
| DERIVATIVES OF 7-HYDROXYCOUMARIN CONTAINING MONOTERPENOID RESIDUES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS (RSV) REPRODUCTION | 2022 |
|
RU2787352C1 |
| CHIRAL γ-KETOSULFANYL DERIVATIVES OF PINANE STRUCTURE AND THEIR PRODUCTION METHOD | 2021 |
|
RU2783164C1 |
| CHIRAL MYRTANYL SULPHONAMIDES | 2019 |
|
RU2725878C1 |
| CHIRAL Γ-KETOSULPHONYL DERIVATIVES OF THE PINANE STRUCTURE AND METHOD FOR PRODUCTION THEREOF | 2021 |
|
RU2780452C1 |
| AGENT FOR INHIBITING HUMAN ENZYME TYROSYL-DNA-PHOSPHODIESTERASE 1 BASED ON PHENYLCOUMARINES, SENSITIZING TUMORS TO ANTITUMOUR AGENTS | 2019 |
|
RU2724878C1 |
| CHIRAL MONOTERPENE SULFINAMIDES | 2017 |
|
RU2646959C1 |
