METHOD FOR SELECTING INDIGENOUS STRAINS OF HUMAN INTESTINAL BIFIDOBACTERIA FOR THEIR INCLUSION IN PROBIOTIC PREPARATIONS Russian patent published in 2023 - IPC C12N1/20 C12Q1/00 A61K35/745 

Abstract RU 2806579 C2

FIELD: biotechnology; medicine.

SUBSTANCE: method has been proposed for selecting indigenous strains of human intestinal bifidobacteria for their inclusion in probiotic preparations. The method involves preliminary obtaining isolates of these bacteria. The selection of bacteria is carried out by assessing their persistent properties, namely antilysozyme activity and biofilm-forming ability. Bacteria are selected with an antilysozyme activity value greater than 1.5 μg/ml⋅of OP450 and biofilm formation over 0.35 units of OP630.

EFFECT: indigenous strains of bifidobacteria, selected by the proposed method, are characterized by a high level of viable cells in the human intestine.

1 cl, 3 tbl, 1 ex

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RU 2 806 579 C2

Authors

Bukharin Oleg Valerevich

Ivanova Elena Valerevna

Perunova Natalya Borisovna

Dates

2023-11-01Published

2023-04-11Filed