N-(1H-IMIDAZOL-2-YL)BENZAMIDE AND PHARMACEUTICAL COMPOSITION CONTAINING IT AS ACTIVE INGREDIENT Russian patent published in 2023 - IPC C07D403/12 C07D401/14 C07D403/14 C07D405/14 C07D413/12 C07D417/12 C07D417/14 A61K31/4178 A61K31/422 A61K31/4439 A61K31/454 A61P35/00 A61P37/00 

Abstract RU 2806754 C1

FIELD: pharmaceutical composition.

SUBSTANCE: invention is related to N-(1H-imidazol-2-yl)benzamide of formula (I), where the values of R1-R 4, A, X are defined in the formula of the invention, or a pharmaceutically acceptable salt or stereoisomer thereof, which has inhibitory activity in relation to IRAK-4.

EFFECT: used for the effective prevention and treatment of diseases mediated by IRAK-4 receptors, in particular autoimmune diseases or lymphomas.

19 cl, 26 tbl, 303 ex

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RU 2 806 754 C1

Authors

Chung, Jaeuk

Kim, Sunmi

Cho, Hanyang

Min, Jiyoung

Dates

2023-11-07Published

2020-09-29Filed