USE OF TRADIPITANT FOR MOTION SICKNESS Russian patent published in 2023 - IPC A61K31/4192 A61K31/444 A61P1/08 

FIELD: pharmaceuticals.

SUBSTANCE: group of inventions relates to the field of treatment or prevention of motion sickness or its symptoms. The following is proposed: the use of tradipitant, as well as the use of a pharmaceutical composition containing tradipitant or a pharmaceutically acceptable salt thereof, in the treatment or prevention of motion sickness or a symptom thereof in an individual, where the individual is a human. The said treatment or prevention includes the following: administering tradipitant or a pharmaceutical composition containing tradipitant or a pharmaceutically acceptable salt thereof to an individual in an amount effective to treat or prevent motion sickness or a symptom of motion sickness in the individual. An effective amount of tradipitant may be, for example, 100–400 mg, in particular about 170 mg. An effective amount can be administered as a single dose, such as a single oral dose, which can be administered before the onset of motion causing nausea, typically about 30 minutes before the onset of such motion, or after the onset of symptoms of motion sickness.

EFFECT: use of a group of inventions can prevent or reduce the severity or frequency of one or more symptoms of motion sickness, including the prevention of nausea, vomiting, dizziness, headache, fullness, cold sweats, sweating, paleness or confusion.

25 cl, 6 dwg, 6 tbl, 3 ex