NEW MACROCYCLIC DERIVATIVES, THEIR PRODUCTION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Russian patent published in 2023 - IPC C07D498/22 A61K31/407 A61P35/00 

Abstract RU 2808689 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound of formula (I), a pharmaceutical composition, as well as the use of a compound of formula (I) for the manufacture of a medicinal product for the treatment of Bcl-2-mediated malignancy.

EFFECT: obtaining compounds that have inhibitory activity against Bcl-2 protein and can be used for the treatment of Bcl-2-mediated malignancy.

15 cl, 2 tbl, 48 ex, 1 dwg

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RU 2 808 689 C2

Authors

Starck Jerome-Benoit

Durand Didier

Chen I-Jen

Le Tiran Arnaud

Ortuno Jean-Claude

Nyerges Miklos

Ligeti Melinda

Fejes Imre

Dates

2023-12-01Published

2018-10-24Filed