FIELD: pharmaceuticals.
SUBSTANCE: invention relates to the use of compounds of the class of 2-azaspiro[3.5]nonan-1-ones, in particular 3,3'-(1,4-phenylene)bis[2-aryl-2-azaspiro[3.5]-nonan-1-ones ], where Ar=4-CH3OS6H4 (a), Ar=Ph (b), Ar=3-ClC6H4 (c), Ar=2.5-(CH3)2C6H4 (d), as agents with antinociceptive activity.
EFFECT: use of 3.3'-(1,4-phenylene)bis[3-aryl-2-azaspiro[3.5]-nonan-1-ones], exhibiting high analgesic activity at a concentration of 50 mg/kg.
1 cl, 1 tbl, 5 ex
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Authors
Dates
2023-12-05—Published
2023-03-23—Filed