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2 798 423

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IPC

C07D487/10(2006-01-01)

A61K31/4188(2006-01-01)

A61P31/06(2006-01-01)

(21) (22)

Application

2023107874, 2023-03-30

(24)

Start date

2023-03-30

(22)

Actual filing date

2023-03-30

(45)

Published

2023-06-22

(72)

Inventor

Maslivets Andrei NikolaevichTretiakov Nikita AlekseevichBalandina Svetlana Iurevna

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniia Gosudarstvennyi Natsionalnyi Issledovatelskii Universitet»

USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYETHYL)-1,3,6-TRIAZASPIRO[4,4]NON-8-EN-2,4,7-TRIONES AS ANTITUBERCULOUS AGENTS Russian patent published in 2023 - IPC C07D487/10 A61K31/4188 A61P31/06

Abstract RU 2798423 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to the new use of 9-aroyl-8-hydroxy-6-(2-hydroxyethyl)-1,3,6-triazaspiro[4,4]non-8-en-2,4,7-trions of the general formula 5a-e, as agents with anti-tuberculosis activity.

where: R = H, Ar = Ph (a), 4-ClC₆H₄ (b); R = Ph, Ar = Ph (c), 4-ClC₆H₄ (d), 4-BrC₆H₄ (e).

EFFECT: effective inhibition of Mycobacterium tuberculosis provided by the compound of the indicated structure 5a-e.

1 cl, 1 tbl, 6 ex

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RU 2 798 423 C1

Authors

Maslivets Andrei Nikolaevich

Tretiakov Nikita Alekseevich

Balandina Svetlana Iurevna

Dates

2023-06-22—Published

2023-03-30—Filed