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(19)

(11)

2 809 320

(13)

(51)

IPC

G09B23/28(2006-01-01)

A61F9/00(2006-01-01)

A61F9/08(2006-01-01)

A61K31/46(2006-01-01)

A61K31/715(2006-01-01)

A61K31/196(2006-01-01)

A61P27/02(2006-01-01)

(21) (22)

Application

2023115927, 2023-06-19

(24)

Start date

2023-06-19

(22)

Actual filing date

2023-06-19

(45)

Published

2023-12-11

(72)

Inventor

Chuprov Aleksandr DmitrievichNotova Svetlana ViktorovnaKim Svetlana MikhailovnaKazakova Tatiana VitalevnaMarshinskaia Olga Vladimirovna

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniia Gosudarstvennyi Universitet»

METHOD FOR MODELING CATARACTS IN LABORATORY RATS Russian patent published in 2023 - IPC G09B23/28 A61F9/00 A61F9/08 A61K31/46 A61K31/715 A61K31/196 A61P27/02

Abstract RU 2809320 C1

FIELD: ophthalmology.

SUBSTANCE: daily ultraviolet irradiation of rats aged 10 months with a wavelength of 300-350 nm and a power of 50 W is carried out at a distance of 30 cm for 20 minutes, lasting 6 months. Before irradiation, double instillation of mydriatics and keratoprotective gel based on sulfated glycosaminoglycans is performed. After irradiation, a tissue repair stimulator based on dexpanthenol is applied.

EFFECT: activating the processes of photo-oxidation and accumulation of photolysis products in lens cells, which serve as a pathogenetic factor in the development of age-related cataracts.

1 cl, 3 dwg, 1 tbl

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RU 2 809 320 C1

Authors

Chuprov Aleksandr Dmitrievich

Notova Svetlana Viktorovna

Kim Svetlana Mikhailovna

Kazakova Tatiana Vitalevna

Marshinskaia Olga Vladimirovna

Dates

2023-12-11—Published

2023-06-19—Filed