FIELD: medical biotechnology and immunology.
SUBSTANCE: following is proposed: a vaccine for the prevention or treatment of coronavirus infection such as COVID-19 and its use to induce an immune response. The vaccine contains the nCoV-19/Russia/SP48-1339/2021 strain of the SARS-Cov-2 virus, deposited in a specialized collection of reference cultures of strains of pathogenicity groups II-IV (arboviruses and others) of the Federal State Budgetary Institution 48th Central Research Institute of the Russian Ministry of Defense under Registration No. 1339.
EFFECT: vaccine provides high immunogenicity and effectiveness, and the use of optimally low concentrations of adjuvants in combination, primarily CpG-ODN, significantly reduces the safety risks of the medicinal product during wide use.
9 cl, 5 tbl, 4 ex
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