FIELD: biochemistry.
SUBSTANCE: single-domain antibody to STAT3. Also disclosed is an isolated polypeptide, a pharmaceutical composition containing said antibody. A method for diagnosing a STAT3-mediated disorder; a method for preventing or treating a STAT3-mediated disease using said antibody; use of pharmaceutical composition for the treatment of a STAT3-mediated disorder.
EFFECT: ability to effectively treat diseases associated with STAT3.
9 cl, 14 dwg, 41 tbl, 16 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ANTI-MET ANTIBODIES AND THEIR USE | 2017 |
|
RU2765267C2 |
| ANTIBODIES TO PAC1 AND THEIR APPLICATION OPTIONS | 2019 |
|
RU2781553C2 |
| METHODS OF OBTAINING INDUSTRIAL PRODUCTS FROM PLANT LIPIDS | 2015 |
|
RU2743384C2 |
| CHIMERIC ANTIGEN RECEPTORS TARGETING CD70 | 2019 |
|
RU2801824C2 |
| ANTIBODIES TO FACTOR XI | 2017 |
|
RU2800719C2 |
| PLANTS WITH MODIFIED CHARACTERS | 2017 |
|
RU2809117C2 |
| MONOCLONAL ANTIBODY OR ITS ANTIGEN-BINDING FRAGMENT WHICH SPECIFICALLY BINDS TO 4Rα (GD2 GANGLIOSIDE) AND ITS USE | 2021 |
|
RU2808563C2 |
| IMMUNOGLOBULIN WITH TANDEM FAB- FRAGMENTS AND ITS APPLICATION OPTIONS | 2017 |
|
RU2767329C2 |
| CRYOPRESERVED CELLS ARE NATURAL KILLERS PRELOADED WITH ANTIBODY CONSTRUCTION | 2019 |
|
RU2819927C2 |
| BCMA-TARGETED ANTIBODY AND ITS USE | 2018 |
|
RU2799655C2 |
