FIELD: organic chemistry.
SUBSTANCE: invention relates to potassium 2-cyano-4-[6-(4-bromophenyl)-1,6-dioxo-1-methoxy-4-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)amino]hexa-2,4-dien-3-olate (1).
EFFECT: obtaining a compound of formula 1 with pronounced analgesic activity and low toxicity.
1 cl, 1 tbl, 3 ex
| Title |
Year |
Author |
Number |
| 2-CYANO-4-[1,6-DIOXO-6-(4-METHYLPHENYL)-1-ETOXY-4-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-IL)AMINO]HEXA-2,4-DIEN-3-OLATE POTASSIUM WITH ANALGESIC ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Kozlov Danil Anatolevich
|
RU2798429C1 |
| OBTAINING 6-(4-BROMOPHENYL)-6-OXO-1-(PHENYLIMINO)-2-CYANO-4-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-YL)AMINO)-1-ETOXYHEXA-2,4-DIENE-3-OLATE POTASSIUM WITH ANALGESIC ACTIVITY |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Silaichev Pavel Sergeevich
|
RU2808997C1 |
| 1-AMINO-1,6-DIOXO-6-(4-CHLOROPHENYL)-2-CYANO-4-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)HEXA -2,4-DIEN-3-OLATE POTASSIUM WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Kozlov Danil Anatolevich
|
RU2798468C1 |
| APPLICATION OF AN ANALGESIC AGENT BASED ON POTASSIUM 1,6-DIOXO-6-(4-CHLOROPHENYL)-2-CYANO-1-ETHOXY-4-[((3-ETHOXYCARBONYL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHENE-2-YL)AMINO]HEXA-2,4-DIENE-3-OLATE |
2021 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgenevich
- Makhmudov Ramiz Ragibovich
- Shipilovskikh Darya Aleksandrovna
|
RU2776070C1 |
| 2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)-4-(4-METHOXYPHENYL)-4-OXOBUTT-2-ENOIC ACID BENZYL ETHER WITH ANALGIC ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
- Sharaveva Iuliia Olegovna
|
RU2798424C1 |
| ETHYL ETHER 2-AMINO-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)-5-(2-(4-ETHYLPHENYL)-2-OXOETHYLIDENE)-4-OXO- 4,5-DIHYDRO-1H-PYRROL-3-CARBOXYLIC ACID WITH ANALGESIC ACTIVITY |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Parkhoma Kseniia Iurevna
|
RU2810070C1 |
| 2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO)-4-(4-METHOXYPHENYL)-4-OXOBUT-2-ENOIC ACID WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
- Sharaveva Iuliia Olegovna
|
RU2784434C1 |
| USE OF CYTOTOXIC AGENTS BASED ON SUBSTITUTED POTASSIUM 1-AMINO-1,6-DIOXO-2-CYANO-1-ETHOXY-6-R1-4-[((3-ETHOXYCARBONYL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO]HEXA-2,4-DIEN-3-OLATES IN TREATMENT OF LUNG MELANOMA |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Timin Aleksandr Sergeevich
|
RU2808533C1 |
| 4-(4-METHOXYPHENYL)-4-OXO-N-PHENYL-2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-YL)AMINO)BUT-2-ENAMIDE WITH ANALGESIC ACTIVITY |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
|
RU2810072C1 |
| 4-OXO-N-(FURAN-2-YLMETHYL)-4-(4-CHLOROPHENYL)-2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)BUT-2-ENAMIDE WITH ANALGESIC ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
- Okoneshnikova Elizaveta Aleksandrovna
|
RU2798425C1 |
