FIELD: organic chemistry.
SUBSTANCE: invention relates to organic chemistry, namely to 1,6-dioxo-1-methoxy-6-phenyl-2-cyano-4-((3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene-2-yl)amino)hexa-2,4-diene-3-olate of potassium (1).
EFFECT: obtaining a compound of formula 1, having pronounced anti-inflammatory activity and low toxicity.
1 cl, 1 tbl, 3 ex
| Title |
Year |
Author |
Number |
| 1-AMINO-1,6-DIOXO-6-(4-CHLOROPHENYL)-2-CYANO-4-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)AMINO)HEXA -2,4-DIEN-3-OLATE POTASSIUM WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Kozlov Danil Anatolevich
|
RU2798468C1 |
| SODIUM 1-AMINO-1,6-DIOXO-6-(P-TOLYL)-2-CYANO-4-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-YL)AMINO)HEXA-2,4-DIENE-3-OLATE, HAVING ANALGESIC ACTIVITY |
2024 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
|
RU2831124C1 |
| POTASSIUM 2-(4-BROMOPHENYL)-6-OXO-4-(PHENYLIMINO)-1,6-CYANO-1-((4-CYANO-3-TETRAHYDROBENZO[b]THIOPHEN-4,5,6,7-YL)AMINO)-2-ETOXYHEXA-2,4-DIENE-3-OLATE WITH ANALGESIC ACTIVITY |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
|
RU2810078C1 |
| 2-CYANO-4-[1,6-DIOXO-6-(4-METHYLPHENYL)-1-ETOXY-4-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-IL)AMINO]HEXA-2,4-DIEN-3-OLATE POTASSIUM WITH ANALGESIC ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Kozlov Danil Anatolevich
|
RU2798429C1 |
| APPLICATION OF AN ANALGESIC AGENT BASED ON POTASSIUM 1,6-DIOXO-6-(4-CHLOROPHENYL)-2-CYANO-1-ETHOXY-4-[((3-ETHOXYCARBONYL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHENE-2-YL)AMINO]HEXA-2,4-DIENE-3-OLATE |
2021 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgenevich
- Makhmudov Ramiz Ragibovich
- Shipilovskikh Darya Aleksandrovna
|
RU2776070C1 |
| N'-(IMINO(2-((6-(2-METHOXYPHENYL)-2-(4-NITROBENZOYL)-3-OXO-2,3-DIHYDROPYRIDAZIN-4-YL)AMINO)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-3-YL)METHYL)-4-NITROBENZOHYDRAZIDE, HAVING ANTI-INFLAMMATORY ACTIVITY |
2024 |
- Shipilovskikh Sergej Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrij Vladimirovich
|
RU2831250C1 |
| OBTAINING 6-(4-BROMOPHENYL)-6-OXO-1-(PHENYLIMINO)-2-CYANO-4-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-YL)AMINO)-1-ETOXYHEXA-2,4-DIENE-3-OLATE POTASSIUM WITH ANALGESIC ACTIVITY |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Silaichev Pavel Sergeevich
|
RU2808997C1 |
| 2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO)-4-(4-METHOXYPHENYL)-4-OXOBUT-2-ENOIC ACID WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
- Sharaveva Iuliia Olegovna
|
RU2784434C1 |
| N-(5-BROMOPYRIDIN-2-YL)-4-OXO-4-(P-TOLYL)-2-((3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL) )AMINO)BUT-2-ENAMIDE AS AN ANTI-INFLAMMATORY DRUG |
2022 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Gorbunova Irina Aleksandrovna
- Okoneshnikova Elizaveta Aleksandrovna
|
RU2798426C1 |
| USE OF CYTOTOXIC AGENTS BASED ON SUBSTITUTED POTASSIUM 1-AMINO-1,6-DIOXO-2-CYANO-1-ETHOXY-6-R1-4-[((3-ETHOXYCARBONYL)-4,5,6,7-TETRAHYDROBENZO[b]THIOPHEN-2-yl)AMINO]HEXA-2,4-DIEN-3-OLATES IN TREATMENT OF LUNG MELANOMA |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Timin Aleksandr Sergeevich
|
RU2808533C1 |
