USE OF A DERIVATIVE OF CINNAMIC ACID IN ALZHEIMER'S DISEASE AS A CEREBROPROTECTIVE AGENT THAT REGULATES THE FUNCTION OF VDAC1 Russian patent published in 2023 - IPC A61K31/192 A61P25/28 

Abstract RU 2810301 C2

FIELD: medicine.

SUBSTANCE: invention relates to the use of pharmacologically active compounds for the treatment of neurodegenerative diseases in particular Alzheimer's disease. The invention relates to the use of 4-hydroxy-3,5-di-tert-butyl cinnamic acid (formula I) at a dose of 100 mg/kg orally in Alzheimer's disease as a cerebroprotective agent that regulates the function of VDAC1 channels.

EFFECT: invention provides effective treatment of Alzheimer's disease by using 4-hydroxy-3,5-di-tert-butyl cinnamic acid as a cerebroprotective agent that regulates the function of VDAC1 channels.

1 cl, 1 tbl, 2 ex

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Authors

Pozdnyakov Dmitrij Igorevich

Chernikov Maksim Valentinovich

Dates

2023-12-26Published

2022-04-08Filed