FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to experimental oncology. Male C57BL/6 mice are initially treated with chronic neurogenic pain. After 2 weeks, a suspension of B16/F10 murine melanoma tumor cells in 0.5 ml of saline at a dilution of 1:20 is injected subcutaneously under the scapula on the left. 24 hours after inoculation of B16/F10 melanoma, mice are intraperitoneally injected with freshly isolated mitochondria from the heart of intact rats: 3.3 mg of protein per 1 animal in 0.3 ml of saline, then mitochondrial therapy is carried out daily for 21 days.
EFFECT: invention prevents the development of myocardial infarction.
1 cl, 5 dwg, 1 tbl
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Authors
Dates
2022-12-20—Published
2022-05-06—Filed