COMPOSITION FOR INCREASING EXPRESSION OF PGC-1Α Russian patent published in 2024 - IPC A61K31/702 A61P3/04 A61P3/06 A61P21/00 A61P25/14 A61P25/16 A61P25/18 

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention relates to the field of pharmaceutics and medicine, namely to a method for preventing or treating a disease or symptom associated with a decrease in the expression of coactivator of 1-alpha receptor, activated by peroxisome proliferators (PGC-1α), in a subject, comprising administering a composition containing α-NeuNAc-(2→3)-β-D-Gal-(1→4)-D-Glc and/or α-NeuNAc-(2→6)-β-D-Gal-(1→4)-D-Glc, subject in need thereof, where NeuNAc denotes N-acetylneuraminyl, Gal denotes galactose, Glc denotes glucose, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient, wherein said disease or symptom associated with reduced expression of PGC-1α are selected from Parkinson's disease (PD), Huntington's disease (HD), sarcopenia and cachexia.

EFFECT: increased expression of PGC-1α.

8 cl, 26 dwg, 15 ex