5'-CAP-TRINUCLEOTIDE COMPOUNDS OR 5'-CAP COMPOUNDS WITH LARGE NUMBER OF NUCLEOTIDES AND THEIR USE FOR RNA STABILIZATION, PROTEIN EXPRESSION AND IN THERAPY Russian patent published in 2024 - IPC C12N15/11 C12N5/07 C07H21/02 A61K48/00 A61K31/7088 

Abstract RU 2811940 C2

FIELD: biotechnology.

SUBSTANCE: invention discloses new 5'-cap compounds and can be used to stabilize RNA with such 5'-cap compounds, as well as to increase their expression in cells.

EFFECT: obtaining 5'-cap-trinucleotide compounds or 5'-cap compounds with a large number of nucleotides.

33 cl, 5 dwg, 1 tbl, 5 ex

Similar patents RU2811940C2

Title Year Author Number
METHOD FOR INCREASING RNA EXPRESSION IN CELL 2018
  • Poleganov, Marco Alexander
  • Perkovic, Mario
  • Sahin, Ugur
  • Beissert, Tim
  • Kuhn, Andreas
RU2784654C2
TRANS-REPLICATING RNA 2017
  • Beissert, Tim
  • Sahin, Ugur
  • Perkovic, Mario
RU2752580C2
RNA FOR TREATMENT OF AUTOIMMUNE DISEASES 2018
  • Sahin, Ugur
  • Kreiter, Sebastian
  • Krienke, Christina
  • Petschenka, Jutta
  • Kranz, Lena Mareen
  • Diken, Mustafa
RU2790447C2
COMBINATION OF ANTI-CANCER RNA VACCINE AND PD-1 PATHWAY INHIBITOR AND ITS APPLICATION 2014
  • Fotin-Mlechek Mariola
  • Kallen Karl-Jozef
  • Probst Jokhen
RU2718988C2
RNA REPLICON FOR UNIVERSAL AND EFFECTIVE GENE EXPRESSION 2017
  • Beissert, Tim
  • Sahin, Ugur
  • Perkovic, Mario
RU2748892C2
PRIME-BOOST MODES INVOLVING INTRODUCTION OF AT LEAST ONE MRNA STRUCTURE 2016
  • Fotin-Mlechek Mariola
  • Probst Jokhen
RU2742993C2
VACCINE AGAINST RESPIRATORY SYNCYTIAL VIRUS (RSV) 2014
  • Kramps Tomas
  • Shnee Margit
  • Foss Daniel
  • Pech Benyamin
RU2723328C2
ANTIGEN RECEPTORS AND THEIR APPLICATIONS 2018
  • Voss, Ralf Kholger
  • Sakhin, Ugur
  • Simon, Petra
  • Birtel, Mattias
  • Kaspar, Yanina
RU2794945C2
COMPOSITION FOR TREATING PROSTATE CANCER 2008
  • Probst Jokhen
  • Gerr Ingmar
  • Lander Tomas
RU2583004C2
METHOD FOR INCREASING THE EXPRESSION OF ENCODED RNA PROTEINS 2014
  • Baumkhof Patrik
RU2733424C2

RU 2 811 940 C2

Authors

Kuhn, Andreas

Muramatsu, Hiromi

Kariko, Katalin

Fesser, Stephanie

Sahin, Ugur

Dates

2024-01-19Published

2019-03-14Filed