FIELD: biotechnology.
SUBSTANCE: invention relates to a combination of products containing (a) a nucleic acid with at least one nucleic acid sequence encoding hepatitis D antigen (HDAg) and at least one nucleic acid sequence encoding PreS1; and (b) a polypeptide comprising at least one HDAg polypeptide sequence and at least one PreS1 polypeptide sequence, preferably components (a) and (b) of the said product combination being provided as separate compositions within the said product combination.
EFFECT: invention is effective for inducing an immune response to hepatitis B virus and hepatitis D virus in a subject.
49 cl, 12 dwg, 3 tbl, 10 ex
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